“Ku’upau means to give it everything you have, the pidgin equivalent would be “geev ‘um” or “go for broke”.

In the context of this song, it’s a call for all people of Hawai‘i,
Hawaiian and non-Hawaiian alike to support Hawaiian sovereignty, and to
give it all you have until it is achieved.

It seems there was another question for me in there, but I forget. Oh, yeah, “makuakāne” means “father”.”